It has been a year since the downfall of Hiruma Shigekatsu (Nishida Toshiyuki) who had engaged in dirty hospital politics. Totei University Hospital enters a new era with its first female hospital director Shimura Madoka (Daichi Mao). She touts “Patients first” and presses forward with big reforms to clean up the medical department. However, powerful persons in the hospital start working behind the scenes in an attempt to restore the unchecked powers and “black tower” which controlled the hierarchical society to recapture their own “profits”. While Hiruma acts suspiciously, talented freelance surgeon Daimon Michiko (Yonekura Ryoko) fights the organisation head-on.